Polymer backbone disassembly: polymerisable templates and vanishing supports in high loading parallel synthesis

被引:21
作者
Ball, CP [1 ]
Barrett, AGM [1 ]
Poitout, LF [1 ]
Smith, ML [1 ]
Thorn, ZE [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AY, England
关键词
D O I
10.1039/a806331a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In the synthesis of a library of N-alkyl-3-aza-8-oxabi-cyclo[3.2.1]octane-6,7-dimethanol derivatives, prepared from an 7-oxabicyclo[2.2.1]hept-2-ene-5,6-dimethanol derivative via ring opening metathesis polymerisation using Cl-2(Cy3P)(2)Ru=CHPh, selective alkylation, ozonolytic scission of the polymer backbone and reductive alkylation, purification was facilitated by the differential solubility of the polymer intermediates.
引用
收藏
页码:2453 / 2454
页数:2
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