Ectasia after laser in situ keratomileusis

Eighty-five cases of post laser in situ keratomileusis ectasia were reviewed and analyzed. Cases of keratoconus or forme fruste keratoconus were eliminated; many remaining case reports lacked key information. The current literature is unable to define a specific residual corneal thickness or a range of preoperative corneal thickness that would put an eye at risk for developing ectasia. The most logical cause for eyes without preexisting pathology to develop ectasia is a post-ablation stromal thickness that is mechanically unstable; this "minimal" thickness is probably specific to each eye. The preoperative and postoperative corneal thickness, measured flap thickness, and microkeratome and laser parameters used in a given case are required to determine the range of residual corneal thickness that puts the eye at risk for developing ectasia. Other as yet undetermined factors may play a role in the development of this complication. (C) 2003 ASCRS and ESCRS.