A combination of dexamethasone and anti-IL-17A treatment can alleviate diesel exhaust particle-induced steroid insensitive asthma

被引：17

作者：

Brandt, Eric B. ^{[1
]}

Hershey, Gurjit K. Khurana ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Dept Pediat, Div Asthma Res, Cincinnati, OH 45229 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2016年 / 138卷 / 03期

关键词：

CELLS;

D O I：

10.1016/j.jaci.2016.03.037

中图分类号：

R392 [医学免疫学];

学科分类号：

100108 [医学免疫学];

摘要：

[No abstract available]

引用

收藏

页码：924 / +

页数：8

相关论文

共 9 条

[1]

[Anonymous], 2010, 17 HEI

[2]

Severe Asthma: An Expanding and Mounting Clinical Challenge [J].

Bell, Matthew C. ;

Busse, William W. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2013, 1 (02) :110-122

[3]

Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility [J].

Brandt, Eric B. ;

Myers, Jocelyn M. Biagini ;

Acciani, Thomas H. ;

Ryan, Patrick H. ;

Sivaprasad, Umasundari ;

Ruff, Brandy ;

LeMasters, Grace K. ;

Bernstein, David I. ;

Lockey, James E. ;

LeCras, Timothy D. ;

Hershey, Gurjit K. Khurana .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2015, 136 (02) :295-+

[4]

Diesel exhaust particle induction of IL-17A contributes to severe asthma [J].

Brandt, Eric B. ;

Kovacic, Melinda Butsch ;

Lee, Gerald B. ;

Gibson, Aaron M. ;

Acciani, Thomas H. ;

Le Cras, Timothy D. ;

Ryan, Patrick H. ;

Budelsky, Alison L. ;

Hershey, Gurjit K. Khurana .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 132 (05) :1194-+

[5]

Randomized, Double-Blind, Placebo-controlled Study of Brodalumab, a Human Anti-IL-17 Receptor Monoclonal Antibody, in Moderate to Severe Asthma [J].

Busse, William W. ;

Holgate, Stephen ;

Kerwin, Edward ;

Chon, Yun ;

Feng, JingYuan ;

Lin, Joseph ;

Lin, Shao-Lee .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 188 (11) :1294-1302

[6]

IL-17 in Severe Asthma Where Do We Stand? [J].

Chesne, Julie ;

Braza, Faouzi ;

Mahay, Guillaume ;

Brouard, Sophie ;

Aronica, Marc ;

Magnan, Antoine .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190 (10) :1094-1101

[7]

Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma [J].

Irvin, Chaoyu ;

Zafar, Iram ;

Good, James ;

Rollins, Donald ;

Christianson, Christina ;

Gorska, Magdalena M. ;

Martin, Richard J. ;

Alam, Rafeul .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (05) :1175-+

[8]

Aligning mouse models of asthma to human endotypes of disease [J].

Martin, Rebecca A. ;

Hodgkins, Samantha R. ;

Dixon, Anne E. ;

Poynter, Matthew E. .

RESPIROLOGY, 2014, 19 (06) :823-833

[9]

TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice [J].

McKinley, Laura ;

Alcorn, John F. ;

Peterson, Alanna ;

DuPont, Rachel B. ;

Kapadia, Shernaaz ;

Logar, Alison ;

Henry, Adam ;

Irvin, Charles G. ;

Piganelli, Jon D. ;

Ray, Anuradha ;

Kolls, Jay K. .

JOURNAL OF IMMUNOLOGY, 2008, 181 (06) :4089-4097