Developmental Gene Regulation by an Ancient Intercellular Communication System in Social Amoebae

被引：15

作者：

Asghar, Asma ^{[1
]}

Groth, Marco ^{[2
]}

Siol, Oliver ^{[1
]}

Gaube, Friedemann ^{[1
]}

Enzensperger, Christoph ^{[3
]}

Gloeckner, Gernot ^{[4
,5
]}

Winckler, Thomas ^{[1
]}

机构：

[1] Univ Jena, Dept Pharmaceut Biol, Inst Pharm, Sch Biol & Pharm, D-07743 Jena, Germany

[2] Fritz Lipmann Inst, Leibniz Inst Age Res, D-07745 Jena, Germany

[3] Univ Jena, Dept Pharmaceut Med Chem, Inst Pharm, Sch Biol & Pharm, D-07743 Jena, Germany

[4] Berlin Ctr Genom Biodivers Res, D-14195 Berlin, Germany

[5] Leibniz Inst Freshwater Ecol & Inland Fisheries, D-14195 Berlin, Germany

来源：

PROTIST | 2012年 / 163卷 / 01期

关键词：

Social amoebae; acrasin; RNA-seq; quorum sensing; Dictyostelium; DICTYOSTELIUM; ACRASIN; DEGRADATION; PHYLOGENY; RECEPTORS; RESPONSES; EVOLUTION;

D O I：

10.1016/j.protis.2010.12.002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The social amoebae (Dictyostelia) use quorum sensing-like communication systems to coordinate the periodic transition from uni- to multicellularity. The monophyletic descent of the Dictyostelia provides a unique opportunity to study the origin and adaptive evolution of such intercellular communication systems. We determined that the ability of aggregation-competent cells to respond to the intercellular messenger glorin occurred in the most ancient taxa of the Dictyostelia. We show using Illumina sequencing technology that glorin mediates rapid changes in gene expression at the transition from vegetative growth to aggregation. We conclude that peptide-based communication is the most ancient form of intercellular signaling in the evolution of multicellularity in the social amoebae, but has been repeatedly replaced by other communication systems during the monophyletic evolution of the social amoebae. Glorin communication has parallels with quorum sensing in that the molecule diffuses into the field, stimulates gene expression in receptive cells and coordinates a population-wide response. (C) 2011 Elsevier GmbH. All rights reserved.

引用

页码：25 / 37

页数：13

共 27 条

[1] Integration of signaling networks that regulate Dictyostelium differentiation [J].

Aubry, L ;

Firtel, R .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1999, 15 :469-517

[2] SYNTHESIS AND CONFORMATIONAL-ANALYSIS OF THE SLIME-MOLD ACRASIN-GLORIN [J].

BALL, JB ;

CRAIK, DJ ;

ALEWOOD, PF ;

MORRISON, S ;

ANDREWS, PR ;

NICHOLLS, IA .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1989, 42 (12) :2171-2180

[3] Accurate whole human genome sequencing using reversible terminator chemistry [J].

Bentley, David R. ;

Balasubramanian, Shankar ;

Swerdlow, Harold P. ;

Smith, Geoffrey P. ;

Milton, John ;

Brown, Clive G. ;

Hall, Kevin P. ;

Evers, Dirk J. ;

Barnes, Colin L. ;

Bignell, Helen R. ;

Boutell, Jonathan M. ;

Bryant, Jason ;

Carter, Richard J. ;

Cheetham, R. Keira ;

Cox, Anthony J. ;

Ellis, Darren J. ;

Flatbush, Michael R. ;

Gormley, Niall A. ;

Humphray, Sean J. ;

Irving, Leslie J. ;

Karbelashvili, Mirian S. ;

Kirk, Scott M. ;

Li, Heng ;

Liu, Xiaohai ;

Maisinger, Klaus S. ;

Murray, Lisa J. ;

Obradovic, Bojan ;

Ost, Tobias ;

Parkinson, Michael L. ;

Pratt, Mark R. ;

Rasolonjatovo, Isabelle M. J. ;

Reed, Mark T. ;

Rigatti, Roberto ;

Rodighiero, Chiara ;

Ross, Mark T. ;

Sabot, Andrea ;

Sankar, Subramanian V. ;

Scally, Aylwyn ;

Schroth, Gary P. ;

Smith, Mark E. ;

Smith, Vincent P. ;

Spiridou, Anastassia ;

Torrance, Peta E. ;

Tzonev, Svilen S. ;

Vermaas, Eric H. ;

Walter, Klaudia ;

Wu, Xiaolin ;

Zhang, Lu ;

Alam, Mohammed D. ;

Anastasi, Carole .

NATURE, 2008, 456 (7218) :53-59

[4]

Bonner JT, 2009, SOCIAL AMOEBAE: THE BIOLOGY OF CELLULAR SLIME MOLDS, P1

[5] EVIDENCE FOR THE FORMATION OF CELL AGGREGATES BY CHEMOTAXIS IN THE DEVELOPMENT OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM [J].

BONNER, JT .

JOURNAL OF EXPERIMENTAL ZOOLOGY, 1947, 106 (01) :1-26

[6] STUDIES OF CELL-SURFACE GLORIN RECEPTORS, GLORIN DEGRADATION, AND GLORIN-INDUCED CELLULAR-RESPONSES DURING DEVELOPMENT OF POLYSPHONDYLIUM-VIOLACEUM [J].

DEWIT, RJW ;

VANBEMMELEN, MXP ;

PENNING, LC ;

PINAS, JE ;

CALANDRA, TD ;

BONNER, JT .

EXPERIMENTAL CELL RESEARCH, 1988, 179 (02) :332-343

[7]

Dunny GM, 1999, CELL-CELL SIGNALING IN BACTERIA, P1

[8] Regulation of gene expression by cell-to-cell communication: Acyl-homoserine lactone quorum sensing [J].

Fuqua, C ;

Parsek, MR ;

Greenberg, EP .

ANNUAL REVIEW OF GENETICS, 2001, 35 :439-468

[9] Mitochondrial genome evolution in the social amoebae [J].

Heidel, Andrew J. ;

Gloeckner, Gernot .

MOLECULAR BIOLOGY AND EVOLUTION, 2008, 25 (07) :1440-1450

[10] Activated cAMP receptors switch encystation into sporulation [J].

Kawabe, Yoshinori ;

Morio, Takahiro ;

James, John L. ;

Prescott, Alan R. ;

Tanaka, Yoshimasa ;

Schaap, Pauline .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (17) :7089-7094

← 1 2 3 →