Generation and screening of synthetic receptor libraries

被引：32

作者：

de Miguel, YR ^{[1
]}

Sanders, JKM ^{[1
]}

机构：

[1] Univ Cambridge, Cambridge Ctr Mol Recognit, Chem Lab, Cambridge CB2 1EW, England

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1998年 / 2卷 / 03期

关键词：

D O I：

10.1016/S1367-5931(98)80018-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Efficient methods for the preparation of combinatorial libraries of receptors have been reported recently and, in most cases, these have led to the identification of host-like molecules that bind a particular substrate selectively. Dynamic libraries of macrocycles have also been synthesised that could open the way to a new selection approach to receptors and catalysts.

引用

页码：417 / 421

页数：5

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