Impact of prolonged walking exercise on cardiac structure and function in cardiac patients versus healthy controls

被引:7
作者
Benda, Nathalie M. M. [1 ]
Hopman, Maria T. E. [1 ]
van Dijk, Arie P. J. [2 ]
Oxborough, David [3 ]
George, Keith P. [3 ]
Thijssen, Dick H. J. [1 ,3 ]
Eijsvogels, Thijs M. H. [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Dept Physiol, Radboud Inst Hlth Sci, Philips van Leydenlaan 15, NL-6525 EX Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Cardiol, Radboud Inst Hlth Sci, Nijmegen, Netherlands
[3] Liverpool John Moores Univ, Res Inst Sport & Exercise Sci, Liverpool L3 5UX, Merseyside, England
关键词
Endurance exercise; heart failure; echocardiography; cardiovascular disease; HEART-FAILURE ASSOCIATION; VENTRICULAR DYSFUNCTION; CARDIOVASCULAR-DISEASE; EUROPEAN ASSOCIATION; DIASTOLIC FUNCTION; PHYSICAL-ACTIVITY; TROPONIN-I; METAANALYSIS; PREVENTION; RELEASE;
D O I
10.1177/2047487316631389
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background and design Previous studies have demonstrated that endurance exercise can cause an acute transient decrease in cardiac function in healthy subjects. Whether this also occurs in cardiac patients is unknown. We investigated the impact of prolonged single day and three-day walking exercise on cardiac function and cardiac biomarkers between cardiac patients and healthy controls in an observational study. Methods We recruited 10 cardiac patients (nine males, one female, 685 years) and 10 age- and sex-matched healthy control subjects (nine males, one female, 684 years) to perform 30 or 40km of walking exercise per day for three consecutive days. Cardiac function was examined using echocardiography and cardiac biomarkers (cardiac troponin and B-type natriuretic peptide) with blood samples. Data were collected before walking and directly after walking on day 1 and day 3. Results Post-exercise early systolic tissue contraction velocity of the left ventricle (p=0.005) and global longitudinal left ventricle strain (P=0.026) were increased in both groups compared with baseline. Post-exercise right ventricle peak early diastolic tissue filling velocity and systolic blood pressure/left ventricle end-systolic volume ratio decreased in both groups (p=0.043 and p=0.028, respectively). Post-exercise cardiac troponin levels increased (p=0.045) but did not differ across groups (p=0.60), whereas B-type natriuretic peptide levels did not change (p=0.43). Conclusion This study suggests that stable cardiac patients are capable of performing three days of prolonged walking exercise without clinically significant acute overall deterioration in cardiac function or more pronounced increase in cardiac biomarkers compared with healthy controls.
引用
收藏
页码:1252 / 1260
页数:9
相关论文
共 33 条
[1]
CARDIAC TROPONIN-I - A MARKER WITH HIGH SPECIFICITY FOR CARDIAC INJURY [J].
ADAMS, JE ;
BODOR, GS ;
DAVILAROMAN, VG ;
DELMEZ, JA ;
APPLE, FS ;
LADENSON, JH ;
JAFFE, AS .
CIRCULATION, 1993, 88 (01) :101-106
[2]
A meta-analysis of the prognostic significance of cardiopulmonary exercise testing in patients with heart failure [J].
Cahalin, Lawrence P. ;
Chase, Paul ;
Arena, Ross ;
Myers, Jonathan ;
Bensimhon, Daniel ;
Peberdy, Mary Ann ;
Ashley, Euan ;
West, Erin ;
Forman, Daniel E. ;
Pinkstaff, Sherry ;
Lavie, Carl J. ;
Guazzi, Marco .
HEART FAILURE REVIEWS, 2013, 18 (01) :79-94
[3]
Cardiovascular disease 2005 - the global picture [J].
Callow, Allan D. .
VASCULAR PHARMACOLOGY, 2006, 45 (05) :302-307
[4]
Transient right but not left ventricular dysfunction after strenuous exercise at high altitude [J].
DavilaRoman, VG ;
Guest, TM ;
Tuteur, PG ;
Rowe, WJ ;
Ladenson, JH ;
Jaffe, AS .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 30 (02) :468-473
[5]
Does the human heart fatigue subsequent to prolonged exercise? [J].
Dawson, E ;
George, K ;
Shave, R ;
Whyte, G ;
Ball, D .
SPORTS MEDICINE, 2003, 33 (05) :365-380
[6]
Cardiac drift during prolonged exercise with echocardiographic evidence of reduced diastolic function of the heart [J].
Dawson, EA ;
Shave, R ;
George, K ;
Whyte, G ;
Ball, D ;
Gaze, D ;
Collinson, P .
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2005, 94 (03) :305-309
[7]
DIFFERENT EFFECTS OF PROLONGED EXERCISE ON THE RIGHT AND LEFT-VENTRICLES [J].
DOUGLAS, PS ;
OTOOLE, ML ;
HILLER, WDB ;
REICHEK, N .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1990, 15 (01) :64-69
[8]
DUBOIS D, 1989, NUTRITION, V5, P303
[9]
BODY FAT ASSESSED FROM TOTAL-BODY DENSITY AND ITS ESTIMATION FROM SKINFOLD THICKNESS - MEASUREMENTS ON 481 MEN AND WOMEN AGED FROM 16 TO 72 YEARS [J].
DURNIN, JVGA ;
WOMERSLEY, J .
BRITISH JOURNAL OF NUTRITION, 1974, 32 (01) :77-97
[10]
Effect of Prolonged Walking on Cardiac Troponin Levels [J].
Eijsvogels, Thijs ;
George, Keith ;
Shave, Rob ;
Gaze, David ;
Levine, Benjamin D. ;
Hopman, Maria T. E. ;
Thijssen, Dick H. J. .
AMERICAN JOURNAL OF CARDIOLOGY, 2010, 105 (02) :267-272