The incidence of mental and behavioral disturbances in dementia: The cache county study

被引：82

作者：

Steinberg, M ^{[1
]}

Sheppard, JM ^{[1
]}

Tschanz, JT ^{[1
]}

Norton, MC ^{[1
]}

Steffens, DC ^{[1
]}

Breitner, JCS ^{[1
]}

Lyketsos, CG ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2003年 / 15卷 / 03期

关键词：

D O I：

10.1176/appi.neuropsych.15.3.340

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A population-based prevalence sample of 355 residents of Cache County, Utah, who were diagnosed with dementia, was rated on the Neuropsychiatric Inventory (NPI). Of the 355 residents, 119 had no neuropsychiatric symptoms at baseline and were, consequently, at risk for incident mental and behavioral disturbances. The NPI was read-ministered approximately 18 months later to 61 surviving participants. Sixty-nine percent developed at least one mental or behavioral symptom. Delusions were most common (28%), followed by apathy (21%), and aberrant motor behavior (21%). When this incidence rate of 69% was combined with a previously estimated prevalence rate of 61%, the cumulative 18-month prevalence approached 90%. These results argue for a routine assessment of psychiatric disturbances in all patients with dementia, even among those who have never experienced symptoms of mental or behavioral disturbances.

引用

页码：340 / 345

页数：6

共 34 条

[1]

Bolla LR, 2000, GERIATRICS, V55, P34

[2] APOE-ε4 count predicts age when prevalence of AD increases, then declines -: The Cache County Study [J].