The rise and fall of deleterious mutation

被引:18
作者
Balbi, Kevin J. [1 ]
Feil, Edward J. [1 ]
机构
[1] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
基金
英国生物技术与生命科学研究理事会;
关键词
bacterial adaptation; deleterious mutation; genomic islands;
D O I
10.1016/j.resmic.2007.09.005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:779 / 786
页数:8
相关论文
共 64 条
[1]   Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis [J].
Akashi, H ;
Gojobori, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (06) :3695-3700
[2]   Comparative genomics of microbial pathogens and symbionts [J].
Andersson, SGE ;
Alsmark, C ;
Canbäck, B ;
Davids, W ;
Frank, C ;
Karlberg, O ;
Klasson, L ;
Antoine-Legault, B ;
Mira, A ;
Tamas, I .
BIOINFORMATICS, 2002, 18 :S17-S17
[3]  
BIRKY CW, 1983, GENETICS, V103, P513
[4]   Reductive genome evolution from the mother of Rickettsia [J].
Blanc, Guillaume ;
Ogata, Hiroyuki ;
Robert, Catherine ;
Audic, Stephane ;
Suhre, Karsten ;
Vestris, Guy ;
Claverie, Jean-Michel ;
Raoult, Didier .
PLOS GENETICS, 2007, 3 (01) :0103-0114
[5]   Evolution of amino acid frequencies in proteins over deep time: Inferred order of introduction of amino acids into the genetic code [J].
Brooks, DJ ;
Fresco, JR ;
Lesk, AM ;
Singh, M .
MOLECULAR BIOLOGY AND EVOLUTION, 2002, 19 (10) :1645-1655
[6]   Massive gene decay in the leprosy bacillus [J].
Cole, ST ;
Eiglmeier, K ;
Parkhill, J ;
James, KD ;
Thomson, NR ;
Wheeler, PR ;
Honoré, N ;
Garnier, T ;
Churcher, C ;
Harris, D ;
Mungall, K ;
Basham, D ;
Brown, D ;
Chillingworth, T ;
Connor, R ;
Davies, RM ;
Devlin, K ;
Duthoy, S ;
Feltwell, T ;
Fraser, A ;
Hamlin, N ;
Holroyd, S ;
Hornsby, T ;
Jagels, K ;
Lacroix, C ;
Maclean, J ;
Moule, S ;
Murphy, L ;
Oliver, K ;
Quail, MA ;
Rajandream, MA ;
Rutherford, KM ;
Rutter, S ;
Seeger, K ;
Simon, S ;
Simmonds, M ;
Skelton, J ;
Squares, R ;
Squares, S ;
Stevens, K ;
Taylor, K ;
Whitehead, S ;
Woodward, JR ;
Barrell, BG .
NATURE, 2001, 409 (6823) :1007-1011
[7]   Evidence for genetic drift in the diversification of a geographically isolated population of the hyperthermophilic archaeon Pyrococcus [J].
Escobar-Páramo, P ;
Ghosh, S ;
DiRuggiero, J .
MOLECULAR BIOLOGY AND EVOLUTION, 2005, 22 (11) :2297-2303
[8]   Quantifying the slightly deleterious mutation model of molecular evolution [J].
Eyre-Walker, A ;
Keightley, PD ;
Smith, NGC ;
Gaffney, D .
MOLECULAR BIOLOGY AND EVOLUTION, 2002, 19 (12) :2142-2149
[9]   Small change: Keeping pace with microevolution [J].
Feil, EJ .
NATURE REVIEWS MICROBIOLOGY, 2004, 2 (06) :483-495
[10]   How clonal is Staphylococcus aureus? [J].
Feil, EJ ;
Cooper, JE ;
Grundmann, H ;
Robinson, DA ;
Enright, MC ;
Berendt, T ;
Peacock, SJ ;
Smith, JM ;
Murphy, M ;
Spratt, BG ;
Moore, CE ;
Day, NPJ .
JOURNAL OF BACTERIOLOGY, 2003, 185 (11) :3307-3316