Seroprevalence and incidence of Toxoplasma gondii infection in the Legnano area of Italy

被引:34
作者
De Paschale, M. [1 ]
Agrappi, C. [1 ]
Clerici, P. [1 ]
Mirri, P. [1 ]
Manco, M. T. [1 ]
Cavallari, S. [1 ]
Vigano, E. F. [1 ]
机构
[1] Hosp Legnano, Microbiol Unit, I-20025 Milan, Italy
关键词
antibodies; incidence; pregnancy; screening; seroprevalence; Toxoplasma;
D O I
10.1111/j.1469-0691.2007.01883.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The decreasing prevalence of anti-Toxoplasma antibodies in Europe has re-opened the question of the appropriateness of serological screening during pregnancy. A study of 3426 pregnant women, resident in the Legnano area of Italy, revealed that the IgG seroprevalence according to ELISA was 21.5%, and that of IgM according to ELISA and enzyme-linked fluorescent assay was 1.2% and 0.9%, respectively. The incidence of infection, estimated on the basis of IgG avidity, was 0.9%. These results confirm a decrease in the prevalence of IgG, but indicate a high incidence of infection, thus suggesting that screening for anti-Toxoplasma antibodies during pregnancy should be maintained.
引用
收藏
页码:186 / 189
页数:5
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