Abnormal somatosensory homunculus in dystonia of the hand

被引：270

作者：

Bara-Jimenez, W ^{[1
]}

Catalan, MJ ^{[1
]}

Hallett, M ^{[1
]}

Gerloff, C ^{[1
]}

机构：

[1] NINDS, Human Motor Control Sect, Med Neurol Branch, NIH, Bethesda, MD 20892 USA

来源：

ANNALS OF NEUROLOGY | 1998年 / 44卷 / 05期

关键词：

D O I：

10.1002/ana.410440520

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Abnormalities of the sensory system have been proposed as causative factors for dystonia By mapping the human cortical hand somatosensory area of 6 patients with focal dystonia of the hand, we found an abnormality of the normal homuncular organization of the finger representations in the primary somatosensory cortex (S1). Although a remote antecedent event or even a developmental anomaly cannot entirely be ruled out, our findings may support the concept that abnormal plasticity is involved in the development of dystonia.

引用

页码：828 / 831

页数：4

共 20 条

[1] PREOPERATIVE LOCALIZATION OF THE CENTRAL SULCUS BY DIPOLE SOURCE ANALYSIS OF EARLY SOMATOSENSORY-EVOKED POTENTIALS AND 3-DIMENSIONAL MAGNETIC-RESONANCE-IMAGING
BUCHNER, H
ADAMS, L
KNEPPER, A
RUGER, R
LABORDE, G
GILSBACH, JM
LUDWIG, I
REUL, J
SCHERG, M
[J]. JOURNAL OF NEUROSURGERY, 1994, 80 (05) : 849 - 856
[2] SOMATOTOPY OF HUMAN HAND SOMATOSENSORY CORTEX REVEALED BY DIPOLE SOURCE ANALYSIS OF EARLY SOMATOSENSORY-EVOKED POTENTIALS AND 3D-NMR TOMOGRAPHY
BUCHNER, H
ADAMS, L
MULLER, A
LUDWIG, I
KNEPPER, A
THRON, A
NIEMANN, K
SCHERG, M
[J]. EVOKED POTENTIALS-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1995, 96 (02): : 121 - 134
[3] Buchner Helmut, 1995, Brain Topography, V8, P137, DOI 10.1007/BF01199777
[4] VALIDITY AND RELIABILITY OF A RATING-SCALE FOR THE PRIMARY TORSION DYSTONIAS
BURKE, RE
FAHN, S
MARSDEN, CD
BRESSMAN, SB
MOSKOWITZ, C
FRIEDMAN, J
[J]. NEUROLOGY, 1985, 35 (01) : 73 - 77
[5] A primate genesis model of focal dystonia and repetitive strain injury .1. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys
Byl, NN
Merzenich, MM
Jenkins, WM
[J]. NEUROLOGY, 1996, 47 (02) : 508 - 520
[6] Cohen L G, 1993, Adv Neurol, V63, P187
[7] HAND CRAMPS - CLINICAL-FEATURES AND ELECTROMYOGRAPHIC PATTERNS IN A FOCAL DYSTONIA
COHEN, LG
HALLETT, M
[J]. NEUROLOGY, 1988, 38 (07) : 1005 - 1012
[8] EEG localization accuracy improvements using realistically shaped head models
Cuffin, BN
[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1996, 43 (03) : 299 - 303
[9] TOPOGRAPHY OF SCALP RECORDED POTENTIALS-EVOKED BY STIMULATION OF THE DIGITS
DUFF, TA
[J]. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1980, 49 (5-6): : 452 - 460
[10] PHANTOM-LIMB PAIN AS A PERCEPTUAL CORRELATE OF CORTICAL REORGANIZATION FOLLOWING ARM AMPUTATION
FLOR, H
ELBERT, T
KNECHT, S
WIENBRUCH, C
PANTEV, C
BIRBAUMER, N
LARBIG, W
TAUB, E
[J]. NATURE, 1995, 375 (6531) : 482 - 484

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