Archaeal transcriptional regulation - variation on a bacterial theme?

被引：59

作者：

Bell, SD ^{[1
]}

机构：

[1] Hutchinson MRC Res Ctr, Canc Cell Unit, Cambridge CB2 2XZ, England

来源：

TRENDS IN MICROBIOLOGY | 2005年 / 13卷 / 06期

关键词：

D O I：

10.1016/j.tim.2005.03.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There is now an increasing body of data available on the DNA-binding properties of several putative transcriptional regulators in the Archaeal domain of life. The evidence points to simple models of promoter occlusion or facilitated recruitment of basal machinery for repressors and activators, respectively. However, little is known about the co-factor requirements, in vivo mechanisms and targets of many of these regulators. It is anticipated that the application of post-genomic technologies will begin to shed light on this fascinating area.

引用

页码：262 / 265

页数：4

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