A solvent-free synthesis of β-enamino trihalomethyl ketones

被引：18

作者：

Martins, Marcos A. P. ^{[1
]}

Peres, Rodrigo L. ^{[1
]}

Fiss, Gabriela F. ^{[1
]}

Dimer, Frantiescoli A. ^{[1
]}

Mayer, Rodrigo ^{[1
]}

Frizzo, Clarissa P. ^{[1
]}

Marzari, Mara R. B. ^{[1
]}

Zanatta, Nilo ^{[1
]}

Bonacorso, Helio G. ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2007年 / 18卷 / 08期

关键词：

solvent-free; enaminones; enones; trihalomethyl-compounds; green chemistry;

D O I：

10.1590/S0103-50532007000800006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient green procedure to prepare a series of twenty-six 4-amino-1,1,1-trihalo-3-alken-2- ones [CX3C(O)CH=C(R-1)(NRR3)-R-2, where X = F, Cl, R-1 = H, Me, and R-2/R-3 = H/Ph, H/4-F-Ph, H/Bn, H/(CH2)(2)OH, Me/Ph, Me/Bu, Et/Et, -(CH2)(4)-] from the solvent-free reaction of 1,1,1-trihalo- 4-alkoxy-3-alken-2-ones with primary and secondary amines at room temperature for five minutes is reported (yields of 73-99%).

引用

页码：1486 / 1491

页数：6

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