Peripheral T cell survival

被引：95

作者：

Freitas, AA

Rocha, B

机构：

[1] Inst Pasteur, CNRS 1961, Lab Dynam Lymphocytaires, F-75015 Paris, France

[2] Inst Necker, INSERM, U345, F-75015 Paris, France

来源：

CURRENT OPINION IN IMMUNOLOGY | 1999年 / 11卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(99)80026-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T cell survival in the periphery is an active process, depending on continuous TCR engagement by peptide-MHC complexes and/or response to environmental cytokines. Naive T cells require interactions with the MHC restricting element. The survival requirements of memory T cells are as yet insufficiently characterized, but MHC-restricted interactions are not necessary.

引用

收藏

页码：152 / 156

页数：5

相关论文

共 52 条

[1] Positive effects of combined antiretroviral therapy on CD4(+) T cell homeostasis and function in advanced HIV disease [J].

Autran, B ;

Carcelain, G ;

Li, TS ;

Blanc, C ;

Mathez, D ;

Tubiana, R ;

Katlama, C ;

Debre, P ;

Leibowitch, J .

SCIENCE, 1997, 277 (5322) :112-116

[2]

Barthlott T, 1998, J IMMUNOL, V161, P3992

[3] The role of the thymus and recent thymic migrants in the maintenance of the adult peripheral lymphocyte pool [J].

Berzins, SP ;

Boyd, RL ;

Miller, JFAP .

JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (11) :1839-1848

[4] TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host [J].

Beutner, U ;

MacDonald, HR .

INTERNATIONAL IMMUNOLOGY, 1998, 10 (03) :305-310

[5] IS T-CELL MEMORY MAINTAINED BY CROSS-REACTIVE STIMULATION [J].

BEVERLEY, PCL .

IMMUNOLOGY TODAY, 1990, 11 (06) :203-205

[6] Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells [J].

Brocker, T .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (08) :1223-1232

[7] ON THE CELLULAR BASIS OF IMMUNOLOGICAL T-CELL MEMORY [J].

BRUNO, L ;

KIRBERG, J ;

VONBOEHMER, H .

IMMUNITY, 1995, 2 (01) :37-43

[8]

BUDD RC, 1987, J IMMUNOL, V138, P3120

[9] Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection [J].

Busch, DH ;

Pilip, I ;

Pamer, EG .

JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 188 (01) :61-70

[10] Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus in vivo [J].

Callan, MFC ;

Tan, L ;

Annels, N ;

Ogg, GS ;

Wilson, JDK ;

O'Callaghan, CA ;

Steven, N ;

McMichael, AJ ;

Rickinson, AB .

JOURNAL OF EXPERIMENTAL MEDICINE, 1998, 187 (09) :1395-1402

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