Case of a mentally retarded child with non-24 hour sleep-wake syndrome caused by deficiency of melatonin secretion

被引：14

作者：

Akaboshi, S

Inoue, Y

Kubota, N

Takeshita, K

机构：

[1] Tottori Univ, Fac Med, Inst Neurol Sci, Div Child Neurol, Yonago, Tottori 6838504, Japan

[2] Tottori Univ, Fac Med, Dept Neuropsychiat, Yonago, Tottori 6838504, Japan

[3] Tottori Prefectural Kaike Rehabil Ctr Disabled Ch, Dept Paediat, Yonago, Tottori, Japan

来源：

PSYCHIATRY AND CLINICAL NEUROSCIENCES | 2000年 / 54卷 / 03期

关键词：

congenital; melatonin; non-24 hour sleep-walks syndrome; retarded child; sighted;

D O I：

10.1046/j.1440-1819.2000.00723.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A case of a 5-year-old boy with non-24 hour sleep-wake syndrome and mental retardation is reported. His free-running sleep-wake rhythm was remarkably improved by the oral administration of melatonin. The circadian variation in melatonin secretion was extremely low, and circadian rhythm of cortisol, secretion was noted. It was speculated that his non-24 hour sleep-wake syndrome was due to a congenital deficiency of melatonin secretion, and supplemental melatonin therapy proved effective for treating his condition.

引用

页码：379 / 380

页数：2

共 5 条

[1] Borna disease virus infection and negative syndromes in Japanese schizophrenia patients [J].