Immunogenicity of pneumococcal vaccine in heart transplant recipients

被引：51

作者：

Blumberg, EA

Brozena, SC

Stutman, P

Wood, D

Phan, HM

Musher, DM

机构：

[1] Dept Med, Philadelphia, PA USA

[2] MCP Hahnemann Sch Med, Philadelphia, PA USA

[3] Baylor Coll Med, Houston, TX 77030 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2001年 / 32卷 / 02期

关键词：

D O I：

10.1086/318482

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.

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页码：307 / 310

页数：4

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