A novel arsenic containing riboside (arsenosugar) in three species of gastropod

被引:67
作者
Francesconi, KA
Goessler, W
Panutrakul, S
Irgolic, KJ
机构
[1] Odense Univ, Inst Biol, DK-5230 Odense M, Denmark
[2] Karl Franzens Univ Graz, Inst Analyt Chem, A-8010 Graz, Austria
[3] Phuket Marine Biol Ctr, Phuket 83000, Thailand
关键词
arsenic; arsenobetaine; arsenosugars; gastropod; Thais; Morula;
D O I
10.1016/S0048-9697(98)00272-1
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Arsenic compounds in three marine gastropods (Thais bitubercularis, Thais distinguenda, Morula musiva) from Phuket, Thailand were examined by HPLC using ICP-MS as an arsenic specific detector. Aqueous methanol treatment of the freeze-dried samples (initially 112-339 mu g As g(-1) dry mass) extracted > 96% of the total arsenic. HPLC-ICP-MS of the extracts demonstrated the presence of arsenobetaine (93-95% of total extractable arsenic), arsenocholine (3.1-4.6%), tetramethylarsonium ion (0.21-2.2%), two unknown arsenic compounds (each approx. 0.1%), and an unresolved mixture of arsenic compounds (similar to 1%). One of the unknowns was identified as a new natural product, the arsenosugar 2',3'-dihydroxypropyl 5-deoxy-5-trimethylarsonioriboside, by co-chromatography with synthetic material. The presence of these arsenic compounds in the gastropods is consistent with the hypothesis that trimethylated arsenosugars are transformed into arsenobetaine via arsenocholine within animals. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:139 / 148
页数:10
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