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Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels .1. Development of an optical scanner
被引:259
作者:
Gore, JC
Ranade, M
Maryanski, MJ
Schulz, RJ
机构:
[1] YALE UNIV,DEPT APPL PHYS,NEW HAVEN,CT 06510
[2] MGS RES INC,GUILFORD,CT 06437
[3] YALE UNIV,DEPT THERAPEUT RADIOL,NEW HAVEN,CT 06510
关键词:
D O I:
10.1088/0031-9155/41/12/009
中图分类号:
R318 [生物医学工程];
学科分类号:
0831 ;
摘要:
A new method of dosimetry of ionizing radiations has been developed that makes use of tissue-equivalent polymer gels which are capable of recording three-dimensional dose distributions. The dosimetric data stored within the gels are measured using optical tomographic densitometry. The dose-response mechanism relies on the production of light scattering microparticles which result from the polymerization of acrylic comonomers dispersed in the gel. The attenuation of a collimated Light beam caused by scattering in the irradiated optically turbid medium is directly related to the radiation dose over the range 0-10 Gy. An optical scanner has been developed which incorporates an He-Ne laser, photodiode detectors, and a rotating gel platform. Using mirrors mounted on a translating stage, the laser beam scans across the gel between each incremental rotation of the platform. Using the set of optical density projections obtained, a cross sectional image of the radiation field is then reconstructed. Doses in the range 0-10 Gy can be measured to better than 5% accuracy with a spatial resolution approximate to 2 mm using the current prototype scanner. This method can be used for the determination of three-dimensional dose distributions in irradiated gels, including measurements of the complex distributions produced by multi-leaf collimators, dynamic wedge and stereotactic treatments, and for quality assurance procedures.
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页码:2695 / 2704
页数:10
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