Debridement of the noninfected wound

被引：30

作者：

Cornell, Rhonda S. ^{[1
]}

Meyr, Andrew J. ^{[2
]}

Steinberg, John S. ^{[3
,4
]}

Attinger, Christopher E. ^{[5
,6
]}

机构：

[1] Georgetown Univ, Med Ctr, Dept Plast Surg, Washington, DC 20007 USA

[2] Temple Univ, Sch Podiatr Med, Dept Podiatr Surg, Philadelphia, PA 19122 USA

[3] Georgetown Univ, Sch Med, Dept Plast Surg, Washington, DC 20057 USA

[4] Georgetown Univ Hosp, Ctr Wound Healing, Washington, DC USA

[5] Georgetown Univ, Sch Med, Dept Plast & Orthoped Surg, Div Wound Healing, Washington, DC 20057 USA

[6] Georgetown Univ Hosp, Ctr Wound Healing, Washington, DC USA

来源：

JOURNAL OF VASCULAR SURGERY | 2010年 / 52卷

关键词：

DIABETIC FOOT ULCERS; ULTRASOUND THERAPY; NONHEALING WOUNDS; BED PREPARATION; VENOUS ULCERS; LEG ULCERS; FIBROBLASTS; SENESCENCE; SCIENCE; BIOFILMS;

D O I：

10.1016/j.jvs.2010.06.006

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The utility of wound debridement has expanded to include the management of all chronic wounds, even in the absence of infection and gross necrosis. Biofilm, metalloproteases on the wound base, and senescent cells at the wound edge irreversibly change the physiology of wound healing and contribute to a pathologic, chronic inflammatory environment. The objective of this review is to provide surgeons with a baseline understanding of the processes of debridement in the noninfected wound. (J Vase Surg 2010;52:31S-6S.)

引用

页码：31S / 36S

页数：6

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