The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the dog

被引：162

作者：

Cook, J. L. ^{[1
]}

Kuroki, K. ^{[1
]}

Visco, D. ^{[2
]}

Pelletier, J. -P. ^{[3
]}

Schulz, L. ^{[4
]}

Lafeber, F. P. J. G. ^{[5
]}

机构：

[1] Univ Missouri, Comparat Orthopaed Lab, Columbia, MO 65211 USA

[2] Merck & Co Inc, Rahway, NJ 07065 USA

[3] Univ Montreal, Notre Dame Hosp, Univ Montreal Hosp Ctr, Osteoarthrit Res Unit, Montreal, PQ H3C 3J7, Canada

[4] Univ Missouri, Columbia, MO USA

[5] Univ Med Ctr Utrecht, Utrecht, Netherlands

来源：

OSTEOARTHRITIS AND CARTILAGE | 2010年 / 18卷

关键词：

Osteoarthritis; Histology; Canine; Cartilage; Synovium; Meniscus; Bone; ANTERIOR CRUCIATE LIGAMENT; CANINE ARTICULAR-CARTILAGE; COMPLETE MEDIAL MENISCECTOMY; COLLAGEN TYPE-II; SYNOVIAL-FLUID; GROOVE MODEL; POND-NUKI; PROTEOGLYCAN SYNTHESIS; ANIMAL-MODELS; BONE;

D O I：

10.1016/j.joca.2010.04.017

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

The dog is a common model for study of osteoarthritis (OA). Subjective histologic scoring systems have often served as the reference standard for presence and severity of OA However, these scoring systems have perceived shortcomings The system developed for this report attempts to address these shortcomings by providing a standardized methodology for global assessment of the joint, versatility and the potential for relative weighting of pathology, allowing for comparison among time points. studies, and centers, and critical analysis of the system's reliability The proposed system for assessment of canine tissues appears to provide an effective method for global assessment of articular pathology in OA The system is versatile, comprehensive, and reliable and appears to have advantages over conventional scoring systems (C) 2010 Osteoarthritis Research Society International Published by Elsevier Ltd. All rights reserved

引用

页码：S66 / S79

页数：14

共 75 条

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