Genetics of posttraumatic stress disorder: Review and recommendations for future studies

被引：72

作者：

Koenen, Karestan C.

机构：

[1] Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev & Hlth, Boston, MA 02115 USA

[2] Boston Univ, Sch Med, Dept Psychiat, Boston, MA 02215 USA

来源：

JOURNAL OF TRAUMATIC STRESS | 2007年 / 20卷 / 05期

关键词：

D O I：

10.1002/jts.20205

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Posttraumatic stress disorder (PTSD) is common and debilitating. Posttraumatic stress disorder is moderately heritable; however, the role of genetic factors in PTSD etiology has been largely neglected by trauma researchers. The goal of this study is to motivate trauma researchers to reflect on the role genetic variation may play in vulnerability and resilience following trauma exposure. Evidence from family, twin, and molecular genetic studies for genetic influences on PTSD is reviewed. Recommendations for future studies are presented with emphasis on study design and assessment issues particular to the field of trauma and PTSD. Clinical implications of PTSD genetic studies are discussed.

引用

页码：737 / 750

页数：14

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