A network to monitor antimalarial drug resistance: a plan for moving forward

被引：41

作者：

Sibley, Carol Hopkins ^{[1
]}

Barnes, Karen I. ^{[2
]}

Watkins, William M. ^{[3
]}

Plowe, Christopher V. ^{[4
]}

机构：

[1] Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA

[2] Univ Cape Town, Dept Med, Div Clin Pharmacol, ZA-7925 Cape Town, South Africa

[3] Univ Oxford, Nuffield Dept Med, Oxford, England

[4] Univ Maryland, Sch Med, Ctr Vaccine Dev, Baltimore, MD 21201 USA

来源：

TRENDS IN PARASITOLOGY | 2008年 / 24卷 / 01期

关键词：

D O I：

10.1016/j.pt.2007.09.008

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The spread of resistance to antimalarial drugs has required changes in the recommended first-line treatment for falciparum malaria in almost all regions. Most drugs recommended currently are combinations of a long-acting antimalarial and an artemisinin derivative. This article presents the rationale for establishing a web-based, open-access database of antimalarial drug resistance and efficacy: the World Antimalarial Resistance Network (WARN). The goal of this network is to assemble the tools and information that will enable the malaria community to collate, analyze and share contemporary information on antimalarial-drug efficacy in all endemic regions so that decisions on antimalarial-drug use are based on solid evidence.

引用

页码：43 / 48

页数：6

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