Low-dose oral etidronate therapy for immobilization hypercalcaemia associated with Guillain-Barre syndrome

被引：8

作者：

Go, T ^{[1
]}

机构：

[1] Otsu Red Cross Hosp, Dept Paediat, Otsu, Shiga 5208511, Japan

来源：

ACTA PAEDIATRICA | 2001年 / 90卷 / 10期

关键词：

bisphosphonates; bone-specific alkaline phosphatase; etidronate; Guillain-Barre syndrome; immobilization hypercalcaemia;

D O I：

10.1080/080352501317061666

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A low dose of oral etidronate (3.7 mg kg(-1) d(-1)) was administered for immobilization hypercalcaemia associated with Guillain-Barre syndrome in a 12-y-old boy. There was a slight increase in osteoblastic bone formation reflected by alkaline phosphatase and in particular bone-specific alkaline phosphatase during the treatment and serum calcium decreased to the normal range within 2 wk. No adverse side effects were observed and the patient's linear growth subsequently progressed. Conclusion: A low dose of oral etidronate is safe and effective for treatment of immobilization hypercalcaemia in children, without inhibiting bone formation.

引用

页码：1202 / 1204

页数：3

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