Plants, symbiosis and parasites: A calcium signalling connection

被引:301
作者
Harper, JF
Harmon, A
机构
[1] Univ Nevada, Dept Biochem, Reno, NV 89557 USA
[2] Univ Florida, Dept Bot, Gainesville, FL 32611 USA
基金
美国国家科学基金会;
关键词
D O I
10.1038/nrm1679
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A unique family of protein kinases has evolved with regulatory domains containing sequences that are related to Ca2+-binding EF-hands. In this family, the archetypal Ca2+-dependent protein kinases (CDPKs) have been found in plants and some protists, including the malarial parasite, Plasmodium falciparum. Recent genetic evidence has revealed isoform-specific functions for a CDPK that is essential for Plasmodium berghei gametogenesis, and for a related chimeric Ca2+ and calmodulin-dependent protein kinase (CCaMK) that is essential to the formation of symbiotic nitrogen-fixing nodules in plants. In Arabidopsis thaliana, the analysis of 42 isoforms of CDPK and related kinases is expected to delineate Ca2+ signalling pathways in all aspects of plant biology.
引用
收藏
页码:555 / 566
页数:12
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