Does using ethnic specific criteria improve the usefulness of the term metabolic syndrome? controversies and suggestions

被引:17
作者
Banerjee, D.
Misra, A.
机构
[1] Stanford Univ, Sch Med, Div Cardiovasc Dis, Stanford, CA 94305 USA
[2] All India Inst Med Sci, Dept Internal Med, New Delhi, India
[3] SDA, Diabet Fdn India, Ctr Diabet Obes & Cholesterol Disorders, New Delhi, India
关键词
metabolic syndrome; insulin resistance; South Asians; diabetes; cardiovascular diseases; ethnicity;
D O I
10.1038/sj.ijo.0803619
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
The metabolic syndrome (MetS) is an important tool that identifies populations at increased risk for cardiovascular disease (CVD) and type 2 diabetes, targeting them for preventive measures. The criteria for the identification of the MetS were initially constructed from data in Caucasian populations. Recent research suggests that the current criteria for the MetS may not accurately characterize disease risk in non-Caucasian populations, either over or underestimating the risk in certain ethnic groups. Altering the criteria for each population by making ethnic-specific cutoffs as has been done with waist circumference will help in more accurate characterization. Using different combinations of the MetS criteria for different ethnic groups based CVD risk and factor analysis needs consideration. With better characterizations of patient populations, the ultimate goal would be to make MetS more accurate for predicting CVD risk while retaining the ease of screening afforded by the MetS. The proposed alterations of definition and criteria of the MetS would ensure its continued viability and sustainability.
引用
收藏
页码:1340 / 1349
页数:10
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