Evolutionary analysis of tomato Sw-5 resistance-breaking isolates of Tomato spotted wilt virus

被引：94

作者：

Lopez, Carmelo ^{[2
]}

Aramburu, Jose ^{[3
]}

Galipienso, Luis ^{[3
]}

Soler, Salvador ^{[2
]}

Nuez, Fernando ^{[2
]}

Rubio, Luis ^{[1
]}

机构：

[1] IVIA, Valencia 46113, Spain

[2] Univ Politecn Valencia, COMAV, Valencia 46022, Spain

[3] IRTA, Barcelona 08348, Spain

来源：

JOURNAL OF GENERAL VIROLOGY | 2011年 / 92卷

关键词：

OVERCOMING RESISTANCE; MEDIATED RESISTANCE; POSITIVE SELECTION; RNA-POLYMERASE; N PROTEIN; GENE; CAPSICUM; TSWV; TOSPOVIRUS; PEPPER;

D O I：

10.1099/vir.0.026708-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Tomato spotted wilt virus (TSWV) causes severe economic losses in many crops worldwide and often overcomes resistant cultivars used for disease control. Comparison of nucleotide and amino acid sequences suggested that tomato resistance conferred by the gene Sw-5 can be overcome by the amino acid substitution C to Y at position 118 (C118Y) or T120N in the TSWV movement protein, NSm. Phylogenetic analysis revealed that substitution C118Y has occurred independently three times in the studied isolates by convergent evolution, whereas the substitution T120N was a unique event. Analysis of rates of non-synonymous and synonymous changes at individual codons showed that substitution C118Y was positively selected.

引用

页码：210 / 215

页数：6

共 45 条

[1] Breakdown of Host Resistance by Independent Evolutionary Lineages of Beet necrotic yellow vein virus Involves a Parallel C/U Mutation in Its p25 Gene [J].