Cricopharyngeal achalasia is a common cause of dysphagia in patients with mtDNA deletions

被引：27

作者：

Kornblum, C

Broicher, R

Walther, E

Seibel, P

Reichmann, H

Klockgether, T

Herberhold, C

Schröder, R

机构：

[1] Univ Bonn, Dept Neurol, D-53105 Bonn, Germany

[2] Univ Bonn, Dept Otorhinolaryngol, D-53105 Bonn, Germany

[3] Univ Dresden, Dept Neurol, Dresden, Germany

来源：

NEUROLOGY | 2001年 / 56卷 / 10期

关键词：

D O I：

10.1212/WNL.56.10.1409

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To assess dysphagia, the authors examined 12 patients with Kearns-Sayre syndrome (KSS) or chronic progressive external ophthalmoplegia (CPEO) due to mitochondrial DNA (mtDNA) deletion by videofluoroscopy and manometry. Cricopharyngeal achalasia was documented in nine of 12 patients (75%), whereas deglutitive coordination problems were found in one patient. Cricopharyngeal! myotomy may be an effective treatment in selected cases with severe cricopharyngeal obstruction.

引用

页码：1409 / 1412

页数：4

共 10 条

[1]

Blitzer A, 1997, OTOLARYNG HEAD NECK, V116, P328

[2]

Broicher R, 2000, Laryngorhinootologie, V79, P190

[3]

STRUCTURAL ABNORMALITIES OF THE CRICOPHARYNGEUS MUSCLE IN PATIENTS WITH PHARYNGEAL (ZENKERS) DIVERTICULUM [J].