Introduction of SARS in France, March-April, 2003

被引:39
作者
Desenclos, JC [1 ]
van der Werf, S
Bonmarin, I
Levy-Bruhl, D
Yazdanpanah, Y
Hoen, B
Emmanuelli, J
Lesens, O
Dupon, M
Natali, F
Michelet, C
Reynes, J
Guery, B
Larsen, C
Semaille, C
Mouton, Y
Christmann, D
André, M
Escriou, N
Burguière, A
Manuguerra, JC
Coignard, B
Lepoutre, A
Meffre, C
Bitar, D
Decludt, B
Capek, I
Antona, D
Che, D
Herida, M
Infuso, A
Saura, C
Brücker, G
Hubert, B
LeGoff, D
Scheidegger, S
机构
[1] Inst Veille Sanit, Dept Malad Infect, St Maurice, France
[2] Inst Pasteur, Paris, France
[3] CHU Besancon, Besancon, France
[4] CHU Strasbourg, F-67000 Strasbourg, France
[5] CHU Bordeaux, Bordeaux, France
[6] Hop Instruct Armees St Anne, Brest, France
[7] CHU Rennes, Rennes, France
[8] CHU Montpellier, Montpellier, France
[9] Cellule Inter Reg Epidemiol Ouest, Rennes, France
[10] Direct Departemental Act Sanit & Sociale Finister, Rennes, France
[11] DDASS Doubs, Besancon, France
关键词
D O I
10.3201/eid1002.030351
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe severe acute respiratory syndrome (SARS) in France. Patients meeting the World Health Organization definition of a suspected case underwent a clinical, radiologic, and biologic assessment at the closest university-affiliated infectious disease ward. Suspected cases were immediately reported to the Institut de Veille Sanitaire. Probable case-patients were isolated, their contacts quarantined at home, and were followed for 10 days after exposure. Five probable cases occurred from March through April 2003; four were confirmed as SARS coronavirus by reverse transcription-polymerase chain reaction, serologic testing, or both. The index case-patient (patient A), who had worked in the French hospital of Hanoi, Vietnam, was the most probable source of transmission for the three other confirmed cases; two had been exposed to patient A while on the Hanoi-Paris flight of March 22-23. Timely detection, isolation of probable case-patients, and quarantine of their contacts appear to have been effective in preventing the secondary spread of SARS in France.
引用
收藏
页码:195 / 200
页数:6
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