Cytostatic activity of Achillea ageratum L.

被引：21

作者：

Gómez, MA ^{[1
]}

García, MD ^{[1
]}

Sáenz, MT ^{[1
]}

机构：

[1] Univ Seville, Fac Pharm, Pharmacol Lab, E-41012 Seville, Spain

来源：

PHYTOTHERAPY RESEARCH | 2001年 / 15卷 / 07期

关键词：

Achillea ageratum; Hep-2; cells; McCoy cells; antimitotic activity; cytostatic activity; stigmasterol; beta-sitosterol;

D O I：

10.1002/ptr.837

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep-2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6-mercaptopurine (positive control) against both cultures. Stigmasterol and beta -sitosterol, isolated from the chloroform extract, showed a high degree of growth inhibition. Copyright (C) 2001 John Wiley & Sons, Ltd.

引用

页码：633 / 634

页数：2

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