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The science and therapy of glucocorticoid-induced bone loss

被引：171
作者：
Lane, NE
Lukert, B
机构：
[1] Univ Calif San Francisco, Div Rheumatol, San Francisco, CA 94143 USA
[2] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA
来源：
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 1998年 / 27卷 / 02期
关键词：
D O I：
10.1016/S0889-8529(05)70017-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Glucocorticoids are critical in the management of chronic, noninfectious, inflammatory diseases. Bone loss is a II-cost devastating side effect of these powerful medications. Glucocorticoids produce bone loss by altering calcium metabolism suppressing gonadal hormone production, and inhibiting bone formation. Now that the mechanism of glucocorticoid-induced bone loss is understood and effective medications are available, this disease can be prevented and reversed.
引用
收藏
页码：465 / +
页数：20
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