Surgery and transplantation for hepatocellular cancer

被引:50
作者
Wall, WJ [1 ]
Marotta, PJ [1 ]
机构
[1] Univ Western Ontario, Multiorgan Transplant Program, London Hlth Sci Ctr, London, ON N6A 5A5, Canada
关键词
D O I
10.1053/jlts.2000.19010
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1. Curative treatment of hepatocellular carcinoma (HCC) depends on early diagnosis. 2. The cure rate for operable HCC occurring in the absence of cirrhosis is only 10% to 25%. 3. Features of HCC in patients with cirrhosis that are associated with a 5-year survival rate of 75% after liver transplantation include (1) solitary tumor less than 5 cm; (2) 3 or fewer tumors, each less than 3 cm; and (3) absence of vascular invasion. 4. Advanced cirrhosis limits the widespread application of partial hepatectomy to patients with HCC. 5. Neoadjuvant therapy has not yet been proven to improve patient outcome for early-stage HCC that is promptly treated by transplantation.
引用
收藏
页码:S16 / S22
页数:7
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