Treatment of resistant pemphigus vulgaris with an anti-CD20 monoclonal antibody (Rituximab)

被引：61

作者：

Cooper, HL

Healy, E

Theaker, JM

Friedmann, PS

机构：

[1] Southampton Gen Hosp, Dermatopharmacol Dept, Dermatopharmacol Unit, Southampton SO16 6YD, Hants, England

[2] Southampton Gen Hosp, Dept Pathol, Southampton SO16 6YD, Hants, England

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2003年 / 28卷 / 04期

关键词：

D O I：

10.1046/j.1365-2230.2003.01283.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe a 54-year-old man with resistant pemphigus vulgaris. Standard therapies had afforded inadequate control and have been associated with considerable side-effects. The anti-CD20 monoclonal antibody, Rituximab (MabThera, Roche), was trialled with significant benefit. We discuss its potential mechanism of action.

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页码：366 / 368

页数：3

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