Relationship between spinal reflexes and leg motor function in sub-acute and chronic stroke patients

被引：5

作者：

Takahashi, Yoko ^{[1
,2
,3
]}

Kawakami, Michiyuki ^{[2
]}

Mikami, Rena ^{[3
]}

Nakajima, Toshiya ^{[3
]}

Nagumo, Towa ^{[3
]}

Yamaguchi, Tomofumi ^{[1
]}

Honaga, Kaoru ^{[3
,4
]}

Kondo, Kunitsugu ^{[3
]}

Ishii, Ryota ^{[5
]}

Fujiwara, Toshiyuki ^{[1
,4
]}

Liu, Meigen ^{[2
]}

机构：

[1] Juntendo Univ, Dept Phys Therapy, Fac Hlth Sci, 2-1-1 Hongo,Bunkyo Ku, Tokyo 1138421, Japan

[2] Keio Univ, Dept Rehabil Med, Sch Med, 35 Shinanomachi,Shinjuku Ku, Tokyo 1608582, Japan

[3] Tokyo Bay Rehabil Hosp, 4-1-1 Yatsu, Narashino, Chiba 2750026, Japan

[4] Juntendo Univ, Dept Rehabil Med, Grad Sch Med, 2-1-1,Hongo,Bunkyo Ku, Tokyo 1138421, Japan

[5] Univ Tsukuba, Dept Biostat, Fac Med, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan

来源：

CLINICAL NEUROPHYSIOLOGY | 2022年 / 138卷

关键词：

Reciprocal inhibition; Heteronymous facilitation; Heteronymous inhibition; D1; inhibition; Presynaptic inhibition; Spasticity; RECIPROCAL IA INHIBITION; PATTERNED ELECTRICAL-STIMULATION; PRESYNAPTIC INHIBITION; VOLUNTARY CONTRACTION; ASHWORTH SCALE; MUSCLE; FACILITATION; CORD; EXCITABILITY; MOTONEURONS;

D O I：

10.1016/j.clinph.2022.02.025

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

Objective: To assess the relationship between spinal reflexes and motor function in sub-acute (SAS) and chronic stroke (CS) patients. Methods: Twelve SAS and 16 CS patients underwent electrophysiological assessment of heteronymous facilitation (HF), heteronymous inhibition (HI), disynaptic reciprocal inhibition (DRI), and D1 inhibition (D1). The Fugl-Meyer Assessment Lower Extremity (FMA-LE) and modified Ashworth scale (MAS) were assessed. The relationship between spinal reflexes and motor function was examined in a crosssectional manner. SAS patients were also longitudinally evaluated before and after intensive rehabilitation for approximately 2 months. Results: SAS patients with triceps surae muscle spasticity (MAS >= 1) showed higher HF values (p = 0.03) than those without spasticity. SAS patients with quadriceps muscle spasticity showed higher HF values (p < 0.01); patients with hamstring muscle spasticity showed higher DRI value (disinhibition) (p < 0.01) than those without spasticity. CS patients showed no significant correlation between spinal reflexes and motor function. The longitudinal study revealed a significant correlation between increase in D1 inhibition and FMA-LE improvement in SAS patients (r = 0.69). Conclusions: The association between impaired spinal reflexes varies with the stage of stroke; HF and DRI may be spasticity indicators in SAS patients. Significance: Spinal reflexes as potential biomarkers may facilitate tailor-made rehabilitation of stroke patients. (c) 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

引用

页码：74 / 83

页数：10

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[1]

H REFLEX IN NORMAL, SPASTIC, AND RIGID SUBJECTS [J].