Post-kala-azar dermal leishmaniasis as an immune reconstitution inflammatory syndrome in a patient with acquired immune deficiency syndrome

被引：37

作者：

Antinori, S. ^{[1
]}

Longhi, E. ^{[1
]}

Bestetti, G. ^{[1
]}

Piolini, R. ^{[1
]}

Acquaviva, V. ^{[1
]}

Foschi, A. ^{[1
]}

Trovati, S. ^{[1
]}

Parravicini, C. ^{[1
]}

Corbellino, M. ^{[1
]}

Meroni, L. ^{[1
]}

机构：

[1] Univ Milan, Dept Clin Sci L Sacco, Infect & Trop Dis Sect, I-20157 Milan, Italy

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2007年 / 157卷 / 05期

关键词：

HAART; human immunodeficiency virus; immune reconstitution inflammatory syndrome; Leishmania infantum; post-kala azar dermal leishmaniasis;

D O I：

10.1111/j.1365-2133.2007.08157.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL) observed mainly in Sudan and India where it follows treated VL in 50% and 10% of cases, respectively. We report a 46-year-old patient with acquired immune deficiency syndrome who, 7 months after diagnosis of VL, developed PKDL and uveal leishmaniasis following HAART-induced immune recovery. In southern Europe PKDL seems to be an emerging clinical presentation among human immunodeficiency virus (HIV)-infected patients experiencing HAART-induced immune recovery after a previous diagnosis of VL. The best treatment among HIV-infected patients remains to be determined.

引用

页码：1032 / 1036

页数：5

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