Consensus conference: Colorectal cancer screening and surveillance in inflammatory bowel disease

被引:407
作者
Itzkowitz, SH [1 ]
Present, DH [1 ]
机构
[1] CUNY Mt Sinai Sch Med, Dept Med, Div Gastroenterol, Fellowship Program G1, New York, NY 10029 USA
关键词
D O I
10.1097/01.MIB.0000160811.76729.d5
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The idiopathic inflammatory bowel diseases, ulcerative colitis and Crohn's colitis, are associated with an increased risk for developing colorectal cancer. To reduce colorectal cancer mortality in inflammatory bowel disease, most patients and their physicians choose to follow a program of Surveillance colonoscopy in ail attempt to detect early neoplastic lesions at a curable stage. Colectomy is typically reserved for patients whose biopsy findings are indicative of heightened cancer risk based oil interpretation by pathologists. Despite the absence of prospective controlled clinical trials to formally evaluate the benefits, risks, and costs of this approach, enough circumstantial evidence has accrued to warrant its widespread adoption in practice. Nevertheless, no standardized guidelines have yet been Set forth to guide the gastroenterologist in performing Surveillance. A panel of international experts was assembled to develop consensus recommendations for the performance Of surveillance. The findings are presented herein.
引用
收藏
页码:314 / 321
页数:8
相关论文
共 40 条
[1]
Family history as a risk factor for colorectal cancer in inflammatory bowel disease [J].
Askling, J ;
Dickman, PW ;
Karlén, P ;
Broström, O ;
Lapidus, A ;
Löfberg, R ;
Ekbom, A .
GASTROENTEROLOGY, 2001, 120 (06) :1356-1362
[2]
Low grade dysplasia in extensive, long-standing inflammatory bowel disease - A follow-up study [J].
Befrits, R ;
Ljung, T ;
Jaramillo, E ;
Rubio, C .
DISEASES OF THE COLON & RECTUM, 2002, 45 (05) :615-620
[3]
BERNSTEIN CN, 1994, LANCET, V343, P71
[4]
Bernstein CN, 2001, CANCER-AM CANCER SOC, V91, P854, DOI 10.1002/1097-0142(20010215)91:4<854::AID-CNCR1073>3.0.CO
[5]
2-Z
[6]
LOWER GASTROINTESTINAL MALIGNANCY IN CROHNS-DISEASE [J].
CONNELL, WR ;
SHEFFIELD, JP ;
KAMM, MA ;
RITCHIE, JK ;
HAWLEY, PR ;
LENNARDJONES, JE .
GUT, 1994, 35 (03) :347-352
[7]
FACTORS AFFECTING THE OUTCOME OF ENDOSCOPIC SURVEILLANCE FOR CANCER IN ULCERATIVE-COLITIS [J].
CONNELL, WR ;
LENNARDJONES, JE ;
WILLIAMS, CB ;
TALBOT, IC ;
PRICE, AB ;
WILKINSON, KH .
GASTROENTEROLOGY, 1994, 107 (04) :934-944
[8]
Eaden J, 2000, ALIMENT PHARM THERAP, V14, P145
[9]
Guidelines for screening and surveillance of asymptomatic colorectal cancer in patients with inflammatory bowel disease [J].
Eaden, JA ;
Mayberry, JF .
GUT, 2002, 51 :V10-V12
[10]
The risk of colorectal cancer in ulcerative colitis: a meta-analysis [J].
Eaden, JA ;
Abrams, KR ;
Mayberry, JF .
GUT, 2001, 48 (04) :526-535