Retroviral recombination: what drives the switch?

被引：40

作者：

Negroni, M ^{[1
]}

Buc, H ^{[1
]}

机构：

[1] Inst Pasteur, Dept Mol Biol, F-75724 Paris 15, France

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 02期

关键词：

D O I：

10.1038/35052098

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The high rate of recombination in retroviruses is due to the frequent template switching that occurs during reverse transcription. Although the mechanism that leads to this switch is still a matter of debate, there is increasing evidence that specific RNA structures are involved. And the implications might go beyond retroviral genetic variability.

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页码：151 / 155

页数：5

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