Retroviral recombination: what drives the switch?

被引:39
作者
Negroni, M [1 ]
Buc, H [1 ]
机构
[1] Inst Pasteur, Dept Mol Biol, F-75724 Paris 15, France
关键词
D O I
10.1038/35052098
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The high rate of recombination in retroviruses is due to the frequent template switching that occurs during reverse transcription. Although the mechanism that leads to this switch is still a matter of debate, there is increasing evidence that specific RNA structures are involved. And the implications might go beyond retroviral genetic variability.
引用
收藏
页码:151 / 155
页数:5
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