Understanding the role of tumor stem cells in glioblastoma multiforme: a review article

被引：16

作者：

Fatoo, Aalya ^{[1
]}

Nanaszko, Michael J. ^{[1
]}

Allen, Baxter B. ^{[1
]}

Mok, Christina L. ^{[1
]}

Bukanova, Elena N. ^{[1
]}

Beyene, Robel ^{[1
]}

Moliterno, Jennifer A. ^{[1
,2
]}

Boockvar, John A. ^{[1
]}

机构：

[1] Cornell Univ, Weill Cornell Med Coll, Weill Cornell Brain Tumor Ctr, Dept Neurosurg,Neurosurg Lab Translat Stem Cell R, New York, NY 10021 USA

[2] Yale Univ, Sch Med, Dept Neurosurg, New Haven, CT USA

来源：

JOURNAL OF NEURO-ONCOLOGY | 2011年 / 103卷 / 03期

关键词：

Neural stem cells; Glioma; Brain tumors; BINDING PROTEIN MUSASHI-1; EPIDERMAL-GROWTH-FACTOR; TRANS-RETINOIC ACID; INITIATING CELLS; PROSPECTIVE IDENTIFICATION; HEMATOPOIETIC STEM; KINASE INHIBITOR; FACTOR RECEPTOR; OXYGEN-TENSION; GLIOMA GROWTH;

D O I：

10.1007/s11060-010-0406-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

It has been hypothesized that cancer stem cells (CSC) may account for the pathogenesis underlying various tumors, including GBM. Markers of these CSCs can be potentially used as therapeutic targets. In this review, we discuss the most recent information regarding CSCs, their molecular biology and their potential role in GBM.

引用

收藏

页码：397 / 408

页数：12

相关论文

共 113 条

[1]

BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal [J].

Abdouh, Mohamed ;

Facchino, Sabrina ;

Chatoo, Wassim ;

Balasingam, Vijayabalan ;

Ferreira, Jose ;

Bernier, Gilbert .

JOURNAL OF NEUROSCIENCE, 2009, 29 (28) :8884-8896

[2]

Phase Ib Trial of Oncolytic Herpes Virus G207 shows safety of Multiple Injections and Documents Viral Replication [J].

Aghi, Manish K. ;

Chiocca, E. Antonio .

MOLECULAR THERAPY, 2009, 17 (01) :8-9

[3]

HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors [J].

Ahmed, Nabil ;

Salsman, Vita S. ;

Kew, Yvonne ;

Shaffer, Donald ;

Powell, Suzanne ;

Zhang, Yi J. ;

Grossman, Robert G. ;

Heslop, Helen E. ;

Gottschalk, Stephen .

CLINICAL CANCER RESEARCH, 2010, 16 (02) :474-485

[4]

Prospective identification of tumorigenic breast cancer cells [J].

Al-Hajj, M ;

Wicha, MS ;

Benito-Hernandez, A ;

Morrison, SJ ;

Clarke, MF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (07) :3983-3988

[5]

Notch signaling: Cell fate control and signal integration in development [J].

Artavanis-Tsakonas, S ;

Rand, MD ;

Lake, RJ .

SCIENCE, 1999, 284 (5415) :770-776

[6]

Targeting cancer stem cells through L1CAM suppresses glioma growth [J].

Bao, Shideng ;

Wu, Qiulian ;

Li, Zhizhong ;

Sathornsumetee, Sith ;

Wang, Hui ;

McLendon, Roger E. ;

Hjehneland, Anita B. ;

Rich, Jeremy N. .

CANCER RESEARCH, 2008, 68 (15) :6043-6048

[7]

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response [J].

Bao, Shideng ;

Wu, Qiulian ;

McLendon, Roger E. ;

Hao, Yueling ;

Shi, Qing ;

Hjelmeland, Anita B. ;

Dewhirst, Mark W. ;

Bigner, Darell D. ;

Rich, Jeremy N. .

NATURE, 2006, 444 (7120) :756-760

[8]

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor [J].

Bao, Shideng ;

Wu, Qiulian ;

Sathornsumetee, Sith ;

Hao, Yueling ;

Li, Zhizhong ;

Hjelmeland, Anita B. ;

Shi, Oing ;

McLendon, Roger E. ;

Bigner, Darell D. ;

Rich, Jeremy N. .

CANCER RESEARCH, 2006, 66 (16) :7843-7848

[9]

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma [J].

Bar, Eli E. ;

Chaudhry, Aneeka ;

Lin, Alex ;

Fan, Xing ;

Schreck, Karisa ;

Matsui, William ;

Piccirillo, Sara ;

Vescovi, Angelo L. ;

DiMeco, Francesco ;

Olivi, Alessandro ;

Eberharta, Charles G. .

STEM CELLS, 2007, 25 (10) :2524-2533

[10]

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients [J].

Batchelor, Tracy T. ;

Sorensen, A. Gregory ;

di Tomaso, Emmanuelle ;

Zhang, Wei-Ting ;

Duda, Dan G. ;

Cohen, Kenneth S. ;

Kozak, Kevin R. ;

Cahill, Daniel P. ;

Chen, Poe-Jou ;

Zhu, Mingwang ;

Ancukiewicz, Marek ;

Mrugala, Maciej M. ;

Plotkin, Scott ;

Drappatz, Jan ;

Louis, David N. ;

Ivy, Percy ;

Scadden, David T. ;

Benner, Thomas ;

Loeffler, Jay S. ;

Wen, Patrick Y. ;

Jain, Rakesh K. .

CANCER CELL, 2007, 11 (01) :83-95

← 1 2 3 4 5 6 7 8 9 10 →