Somatosensory-evoked potentials are influenced differently by isometric muscle contraction of stimulated and non-stimulated hand in humans

被引:11
作者
Vrána, J [1 ]
Polácek, H [1 ]
Stancák, A [1 ]
机构
[1] Charles Univ Prague, Fac Med 3, Dept Normal Pathol & Clin Physiol, Prague 12000, Czech Republic
关键词
EEG; evoked potentials; SEP; somatosensory; isometric muscle contraction; gating; pain;
D O I
10.1016/j.neulet.2005.06.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Chronic pain is associated with motor dysfunctions, and stimulation of the motor cortex has been shown to alleviate chronic pain. Recently Nakata et al. [Pain 107 (2004) 91-98] showed differentiated patterns of neuromagnetic evoked fields following painful laser stimulation during phasic movements of stimulated and non-stimulated hand. Phasic movements and static contractions differ in their functional activation of the motor cortices. Therefore, we decided to analyze the effects of isometric contractions of intrinsic right and eft hand muscles on cortical sources of somatic-evoked potentials related to a painful galvanic stimulation of the right middle finger. Using patio-temporal source dipole analysis of I I I electroencephalographic signals in 10 right-handed men, source activities were evaluated in the left primary somatosensory cortex (S 1), left (S2(L)) and right (S2(R)) secondary somatosensory cortex, anterior cingulate cortex (ACC) and posterior cingulate cortex (PCC). Ipsilateral hand muscle contraction was associated with a decrease of source activity in S I and with subsequent increases in S2L and the PCC. Contralateral hand muscle contraction was accompanied by a decrease of source activity in bilateral S2 cortices followed by decreases in the S I and anterior cingulate cortex. Results suggest early suppression of source activity in S I during ipsilateral hand muscle contractions and in bilateral S2 during contralateral hand muscle contractions. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:170 / 175
页数:6
相关论文
共 36 条
[1]   EEG source analysis and fMRI reveal two electrical sources in the fronto-parietal operculum during subepidermal finger stimulation [J].
Andrej, S ;
Polácek, H ;
Vrána, J ;
Rachmanová, R ;
Hoechstetter, K ;
Tintera, J ;
Scherg, M .
NEUROIMAGE, 2005, 25 (01) :8-20
[2]   Circuitry and functional aspects of the insular lobe in primates including humans [J].
Augustine, JR .
BRAIN RESEARCH REVIEWS, 1996, 22 (03) :229-244
[3]   The human supplementary motor area-proper does not receive direct somatosensory inputs from the periphery:: data from stereotactic depth somatosensory evoked potential recordings [J].
Barba, C ;
Valeriani, M ;
Restuccia, D ;
Colicchio, G ;
Faraca, G ;
Tonali, P ;
Mauguière, F .
NEUROSCIENCE LETTERS, 2003, 344 (03) :161-164
[4]   The involvement of the posterior cingulate gyrus in phasic pain processing of humans [J].
Bromm, B .
NEUROSCIENCE LETTERS, 2004, 361 (1-3) :245-249
[5]   Effect of isometric contraction on threshold somatosensory evoked potentials [J].
Chuang, TY ;
Robinson, LR ;
Nelson, MR ;
Moss, F ;
Chiou-Tan, FY .
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 1999, 78 (01) :2-6
[6]   LOCALIZATION, TIMING AND SPECIFICITY OF GATING OF SOMATOSENSORY EVOKED-POTENTIALS DURING ACTIVE MOVEMENT IN MAN [J].
COHEN, LG ;
STARR, A .
BRAIN, 1987, 110 :451-467
[7]   Cerebral activation during the exertion of sustained static force in man [J].
Dettmers, C ;
Lemon, RN ;
Stephan, KM ;
Fink, GR ;
Frackowiak, RSJ .
NEUROREPORT, 1996, 7 (13) :2103-2110
[8]  
Efron B., 1994, INTRO BOOTSTRAP, DOI DOI 10.1201/9780429246593
[9]   Common cortical network for first and second pain [J].
Forss, N ;
Raij, TT ;
Seppä, M ;
Hari, R .
NEUROIMAGE, 2005, 24 (01) :132-142
[10]   Modified activation of somatosensory cortical network in patients with right-hemisphere stroke [J].
Forss, N ;
Hietanen, M ;
Salonen, O ;
Hari, R .
BRAIN, 1999, 122 :1889-1899