Prevalence of serotype 19A Streptococcus pneumoniae among isolates from US children in 2005-2006 and activity of faropenem

被引:24
作者
Critchley, Ian A. [1 ]
Jacobs, Michael R. [2 ,3 ]
Brown, Steven D. [4 ]
Traczewski, Maria M. [4 ]
Tillotson, Glenn S. [5 ]
Janjic, Nebojsa [1 ]
机构
[1] Replidyne Inc, Louisville, CO 80027 USA
[2] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ Hosp, Case Med Ctr, Cleveland, OH 44106 USA
[4] Inst Clin Microbiol, Wilsonville, OR 97070 USA
[5] Replidyne Inc, Milford, CT 06460 USA
关键词
D O I
10.1128/AAC.00310-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Of 393 isolates of Streptococcus pneumoniae from U.S. children collected in 2005-2006, nonvaccine serotypes accounted for 89.1%, with serotype 19A the most prevalent, representing 30.5% of all isolates. The MIC,, of faropenem against serotype 19A isolates was 1 mu g/ml, compared to >= 8 mu g/ml against amoxicillin/clavulanate, cefdinir, cefuroxime axetil, and azithromycin.
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页码:2639 / 2643
页数:5
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