Hematologic Parameters and Angiographic Progression of Coronary Atherosclerosis

被引：146

作者：

Kalay, Nihat ^{[1
]}

Dogdu, Orhan ^{[1
]}

Koc, Fatih ^{[2
]}

Yarlioglues, Mikail ^{[1
]}

Ardic, Idris ^{[1
]}

Akpek, Mahmut ^{[1
]}

Cicek, Davran ^{[3
]}

Oguzhan, Abdurrahman ^{[1
]}

Ergin, Ali ^{[1
]}

Kaya, Mehmet G. ^{[1
]}

机构：

[1] Erciyes Univ, Fac Med, Dept Cardiol, TR-38000 Kayseri, Turkey

[2] Gaziosmanpasa Univ, Dept Cardiol, Tokat, Turkey

[3] Baskent Univ, Sch Med, Dept Cardiol, Antalya, Turkey

来源：

ANGIOLOGY | 2012年 / 63卷 / 03期

关键词：

hematologic parameters; neutrophil/lymphocyte ratio; progression; atherosclerosis; DENSITY-LIPOPROTEIN CHOLESTEROL; LIFE-STYLE MODIFICATION; PLAQUE PROGRESSION; ARTERY-DISEASE; MORTALITY; RISK;

D O I：

10.1177/0003319711412763

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Hematologic parameters have prognostic importance in cardiovascular disease. However, the relation between atherosclerosis progression and hematologic parameters is not well defined. A total of 394 patients requiring repeat coronary angiography were included in the study. According to angiography, patients were divided into 2 groups, progressive (n = 196) and nonprogressive (n = 198) diseases. Hematologic parameters including mean platelet volume (MPV) and neutrophil/lymphocyte (N/L) ratio were measured. Glucose, creatinine, and cholesterol were significantly higher in the progressive group. Mean platelet volume count was similar in both groups. The N/L ratio was significantly higher in the progressive group (5.0 +/- 5.1 vs 3.2 +/- 3; P = .001). In multivariate analysis, the N/L ratio was significantly related with progression (relative risk [RR]: 2.267, 95% CI: 1.068-4.815, P = .03). Progression rate was significantly high in patients with high N/L ratio (39% vs 56%). Our results suggest that the N/L ratio is a predictor of progression of atherosclerosis.

引用

页码：213 / 217

页数：5

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