GenBank

被引:401
作者
Benson, Dennis A. [1 ]
Clark, Karen [1 ]
Karsch-Mizrachi, Ilene [1 ]
Lipman, David J. [1 ]
Ostell, James [1 ]
Sayers, Eric W. [1 ]
机构
[1] Natl Lib Med, Natl Ctr Biotechnol Informat, NIH, Bethesda, MD 20894 USA
基金
美国国家卫生研究院;
关键词
ANNOTATION; GROWTH; BLAST;
D O I
10.1093/nar/gku1216
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
GenBank (R) (http://www.ncbi.nlm.nih.gov/genbank/) is a comprehensive databases contains publicly available nucleotide sequences for over 300 000 formally described species. These sequences are obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects, including whole-genome shotgun and environmental sampling projects. Most submissions are made using the web-based BankIt or standalone Sequin programs, and GenBank staff assign accession numbers upon data receipt. Daily data exchange with the European Nucleotide Archive and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through the NCBI Entrez retrieval system, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP.
引用
收藏
页码:D30 / D35
页数:6
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