Methane activation by methane monooxygenase: free radicals, Fe-C bonding, substrate dependent pathways and the role of the regulatory protein

被引：33

作者：

Deeth, RJ

Dalton, H ^{[1
]}

机构：

[1] Univ Warwick, Dept Biol Sci, Coventry CV4 7AL, W Midlands, England

[2] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY | 1998年 / 3卷 / 03期

关键词：

methane monooxygenase; dinuclear iron; C-H activation; Mechanism;

D O I：

10.1007/s007750050236

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanism of C-PI bond activation by soluble methane monooxygenase is discussed in terms of the di-iron active site structure and the possible formation of free radicals versus Fe-C bonds, The mechanistic significance of reactions which depend on the substrate plus the vital in vivo role played by the regulatory protein are described.

引用

页码：302 / 306

页数：5

共 42 条

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