Facile fabrication of nano-hydroxyapatite/silk fibroin composite via a simplified coprecipitation route

被引：38

作者：

Fan, Chunquan ^{[1
]}

Li, Jiashun ^{[1
]}

Xu, Guohua ^{[1
]}

He, Hailong ^{[1
]}

Ye, Xiaojian ^{[1
]}

Chen, Yuyun ^{[2
]}

Sheng, Xiaohai ^{[2
]}

Fu, Jianwei ^{[2
]}

He, Dannong ^{[2
]}

机构：

[1] Second Mil Med Univ, Dept Orthoped Surg, Changzheng Hosp, Shanghai 200003, Peoples R China

[2] Natl Engn Res Ctr Nanotechnol, Shanghai 200241, Peoples R China

来源：

JOURNAL OF MATERIALS SCIENCE | 2010年 / 45卷 / 21期

关键词：

IN-VITRO; NANOCOMPOSITE; MINERALIZATION; NANOPARTICLES; NANOFIBERS; COLLAGEN; FIBERS; FILMS;

D O I：

10.1007/s10853-010-4656-4

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Nano-hydroxyapatite/silk fibroin (n-HA/SF) composite was successfully fabricated based on a simplified coprecipitation route. In detail, the degummed SF was first dissolved in CaCl2 aqueous/ethanol solution without desalting procedure, and then (NH4)(2)HPO4 solution and NH4OH were dropped into the above solution to form n-HA/SF composite. The structure and morphology of n-HA/SF composite were investigated by Transmission electron microscopy, Fourier transform infrared spectrometry, energy dispersive X-Ray spectrum, X-ray diffraction, and thermogravimetric analyses. Results indicate that the inorganic phase is carbonate-substituted HA with low crystallinity and similar to the crystals of human bone. The HA crystals have diameter of around 20-30 nm and length of about 200-500 nm. The content of SF in the composite is about 30%, and the two phases bonded each other strongly. In addition, a formation mechanism of n-HA/SF was proposed.

引用

页码：5814 / 5819

页数：6

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