Target-induced strand release (TISR) from aptamer-DNA duplex: A general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein

被引：54

作者：

Yoshizumi, Jyun ^{[1
]}

Kumamoto, Satoshi ^{[1
]}

Nakamura, Mitsunobu ^{[1
]}

Yamana, Kazushige ^{[1
]}

机构：

[1] Univ Hyogo, Grad Sch Engn, Dept Mat Sci & Chem, Himeji, Hyogo 6712201, Japan

来源：

ANALYST | 2008年 / 133卷 / 03期

关键词：

D O I：

10.1039/b719089c

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We describe a general strategy for electronic aptamer-based biosensor that is based on target-induced strand release (TISR) of a redox-modified aptamer from the aptamer-capture DNA duplex bound on an electrode.

引用

页码：323 / 325

页数：3

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