CT genotype of promotor polymorphism C159T in the CD14 gene is associated with lower prevalence of atopic dermatitis and lower IL-13 production

被引：9

作者：

Lange, J ^{[1
]}

Heinzmann, A ^{[1
]}

Zehle, C ^{[1
]}

Kopp, M ^{[1
]}

机构：

[1] Univ Freiburg, Childrens Hosp, D-79106 Freiburg, Germany

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 2005年 / 16卷 / 05期

关键词：

D O I：

10.1111/j.1399-3038.2005.00277.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：456 / 457

页数：2

共 6 条

[1] A polymorphism* in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E [J].

Baldini, M ;

Lohman, IC ;

Halonen, M ;

Erickson, RP ;

Holt, PG ;

Martinez, FD .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1999, 20 (05) :976-983

[2] A promoter polymorphism in the CD14 gene is associated with elevated levels of soluble CD14 but not with IgE or atopic diseases [J].

Kabesch, M ;

Hasemann, K ;

Schickinger, V ;

Tzotcheva, I ;

Bohnert, A ;

Carr, D ;

Baldini, M ;

Hackstein, H ;

Leupold, W ;

Weiland, SK ;

Martinez, FD ;

Mutius, E ;

Bein, G .

ALLERGY, 2004, 59 (05) :520-525

[3] Association of a promoter polymorphism of the CD14 gene and atopy [J].

Koppelman, GH ;

Reijmerink, NE ;

Stine, OC ;

Howard, TD ;

Whittaker, PA ;

Meyers, DA ;

Postma, DS ;

Bleecker, ER .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (04) :965-969

[4] High interleukin-13 production by phytohaemagglutinin- and Der p 1-stimulated cord blood mononuclear cells is associated with the subsequent development of atopic dermatitis at the age of 3 years [J].

Lange, J ;

Ngoumou, G ;

Berkenheide, S ;

Moseler, M ;

Mattes, J ;

Kuehr, J ;

Kopp, MV .

CLINICAL AND EXPERIMENTAL ALLERGY, 2003, 33 (11) :1537-1543

[5] The C-159T polymorphism in the CD14 promoter is associated with serum total IgE concentration in atopic Chinese children [J].

Leung, TF ;

Tang, NLS ;

Sung, YM ;

Li, AM ;

Wong, GWK ;

Chan, IHS ;

Lam, CWK .

PEDIATRIC ALLERGY AND IMMUNOLOGY, 2003, 14 (04) :255-260

[6] A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity [J].

LeVan, TD ;

Bloom, JW ;

Bailey, TJ ;

Karp, CL ;

Halonen, M ;

Martinez, FD ;

Vercelli, D .

JOURNAL OF IMMUNOLOGY, 2001, 167 (10) :5838-5844

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