Structure elucidation of xanthobaccin A, a new antibiotic produced from Stenotrophomonas sp strain SB-K88

被引：44

作者：

Hashidoko, Y ^{[1
]}

Nakayama, T

Homma, Y

Tahara, S

机构：

[1] Hokkaido Univ, Fac Agr, Kita Ku, Sapporo, Hokkaido 0608589, Japan

[2] Japan Sci & Technol Corp, CREST, Kawaguchi 3320012, Japan

[3] Hokkaido Natl Agr Expt Stn, Upland Agr Res Ctr, Memuro, Hokkaido 0820071, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 15期

关键词：

pyrrolidinones; antifungal; macrocycles; lactam; bacterium;

D O I：

10.1016/S0040-4039(99)00336-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The major antibiotic constituent, xanthobaccin A, was isolated from broth cultures of Stenotrophomonas sp, strain SB-K88 as a major antifungal substance. The structure elucidation by spectroscopic analyses and chemical conversion revealed it to be a new tetramic acid-containing macrocyclic lactam. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2957 / 2960

页数：4

共 7 条

[1] DISCODERMIDE - A NEW BIOACTIVE MACROCYCLIC LACTAM FROM THE MARINE SPONGE DISCODERMIA-DISSOLUTA [J].

GUNASEKERA, SP ;

GUNASEKERA, M ;

MCCARTHY, P .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (16) :4830-4833

[2]

Homma Y., 1993, ANN PHYTOPATHOL SOC, V59, P282

[3] STRUCTURE OF IKARUGAMYCIN, AN ACYLTETRAMIC ACID ANTIBIOTIC POSSESSING A UNIQUE ASYMMETRIC-HYDRINDACENE SKELETON [J].

ITO, S ;

HIRATA, Y .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1977, 50 (07) :1813-1820

[4] NEW ANTIBIOTIC, IKARUGAMYCIN [J].

JOMON, K ;

AJISAKA, M ;

SAKAI, H ;

KURODA, Y .

JOURNAL OF ANTIBIOTICS, 1972, 25 (05) :271-&

[5] CYLINDRAMIDE - CYTOTOXIC TETRAMIC ACID LACTAM FROM THE MARINE SPONGE HALICHONDRIA-CYLINDRATA TANITA AND HOSHINO [J].

KANAZAWA, S ;

FUSETANI, N ;

MATSUNAGA, S .

TETRAHEDRON LETTERS, 1993, 34 (06) :1065-1068

[6]

Nakayama T., 1996, CHEM STUDY BIOL CONT

[7] ALTERAMIDE-A, A NEW TETRACYCLIC ALKALOID FROM A BACTERIUM-ALTEROMONAS SP ASSOCIATED WITH THE MARINE SPONGE HALICHONDRIA-OKADAI [J].

SHIGEMORI, H ;

BAE, MA ;

YAZAWA, K ;

SASAKI, T ;

KOBAYASHI, J .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (15) :4317-4320

← 1 →