Xanthoquinodin B3, a new anticoccidial agent produced by Humicola sp FO-888

被引：42

作者：

Tabata, N ^{[1
]}

Tomoda, H ^{[1
]}

Iwai, Y ^{[1
]}

Omura, S ^{[1
]}

机构：

[1] KITASATO INST,BIOL FUNCT RES CTR,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 03期

关键词：

D O I：

10.7164/antibiotics.49.267

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Xanthoquinodin B3, a new component of anticoccidial xanthoquinodins, which was detected in the culture broth of Humicola sp. FO-888, was isolated by heat treatment of the xanthoquinodins complex. Structural elucidation indicated that xanthoquinodin B3 has the same heterodimer of xanthone- and anthraquinone-derived monomers as other xanthoquinodins. Schizont formation of monensin-resistant Eirner ia tenella in BHK-21 cells was inhibited by xanthoquinodin B3 at concentrations greater than 0.035 mu M.

引用

页码：267 / 271

页数：5

共 4 条

[1]

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[2]

MATUZAKI K, 1993, TETRAHEDRON LETT, V34, P8251

[3]

XANTHOQUINODINS, NEW ANTICOCCIDIAL AGENTS PRODUCED BY HUMICOLA SP - PRODUCTION, ISOLATION AND PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES [J].

TABATA, N ;

SUZUMURA, Y ;

TOMODA, H ;

MASUMA, R ;

HANEDA, K ;

KISHI, M ;

IWAI, Y ;

OMURA, S .

JOURNAL OF ANTIBIOTICS, 1993, 46 (05) :749-755

[4]

STRUCTURE AND BIOSYNTHESIS OF XANTHOQUINODINS, ANTICOCCIDIAL ANTIBIOTICS [J].

TABATA, N ;

TOMODA, H ;

MATSUZAKI, K ;

OMURA, S .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (19) :8558-8564

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