Synthesis of alpha-trifluoromethyl substituted alpha-amino acid derivatives from methyl 3,3,3-trifluoro-2-diazopropionate

被引：61

作者：

Osipov, SN

Sewald, N

Kolomiets, AF

Fokin, AV

Burger, K

机构：

[1] RUSSIAN ACAD SCI,AN NESMEYANOV ORGANOELEMENT CPDS INST,MOSCOW 117813,RUSSIA

[2] UNIV LEIPZIG,INST ORGAN CHEM,D-04103 LEIPZIG,GERMANY

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 05期

关键词：

3,3,3-trifluoro-2-diazopropionate; 1.2]-Stevens rearrangement; α-trifluoromethyl-α-amino acids;

D O I：

10.1016/0040-4039(95)02265-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New derivatives 2-7 of alpha-trifluoromethyl substituted amino acids are synthesized via transformation of ammonium ylides formed on reaction of methyl 3,3,3-trifluoro-2-diazopropionate with amines and amides, respectively.

引用

页码：615 / 618

页数：4

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