Decision-making in ileocecal Crohn's disease management: surgery versus pharmacotherapy

被引：12

作者：

Eshuis, Emma J. ^{[1
,2
]}

Stokkers, Pieter C. F. ^{[2
]}

Bemelman, Willem A. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Surg, NL-1105 AZ Amsterdam, Netherlands

[2] Univ Amsterdam, Acad Med Ctr, Dept Gastroenterol & Hepatol, NL-1105 AZ Amsterdam, Netherlands

来源：

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY | 2010年 / 4卷 / 02期

关键词：

biologic therapy; clinical remission; Crohn's disease; decision-making; ileocecal disease activity; ileocolic resection; INFLAMMATORY-BOWEL-DISEASE; OPEN ILEOCOLIC RESECTION; QUALITY-OF-LIFE; LONG-TERM OUTCOMES; INFLIXIMAB MAINTENANCE; THERAPY; ADALIMUMAB; REMISSION; IMMUNOSUPPRESSION; IMMUNOMODULATORS;

D O I：

10.1586/EGH.10.3

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Ileocecal Crohn's disease (CD) can be treated medically as well as surgically. Both treatment modalities have been improved markedly in the last two decades, making CD more manageable. However, multidisciplinary research, addressing issues such as timing of surgery or medical treatment versus surgery, is scarce. Particularly in limited ileocecal CD, ileocolic resection might be a good alternative to long-term medical therapy. This review discusses the evidence on medical and surgical treatment options for ileocecal CD. It provides an aid in decision-making by discussing a treatment algorithm that can be used until further evidence on treatment is available.

引用

页码：181 / 189

页数：9

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