Nemorosone, the major constituent of floral resins of Clusia rosea

被引：88

作者：

Cuesta-Rubio, O

Velez-Castro, H

Frontana-Uribe, BA

Cárdenas, J

机构：

[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico

[2] Univ La Habana, Inst Farm & Alimentos, Havana 13600, Cuba

[3] Ctr Quim Farmaceut, Havana 13600, Cuba

来源：

PHYTOCHEMISTRY | 2001年 / 57卷 / 02期

关键词：

Clusia rosea; guttiferae; copey; polyisoprenylated benzophenone; nemorosone;

D O I：

10.1016/S0031-9422(00)00510-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nemorosone, the major constituent of the floral resin of Clusia rosea was isolated after exhaustive chromatography. This compound was fully characterized as it is in the nature, without methylation as reported before. A keto-enol equilibrium was observed and both isomers were totally characterized by NMR spectroscopic techniques. The previously announced structure for methylnemorosone was corrected on the basis of application of chemical methylation, high field 2D NMR techniques and NOE difference spectroscopy experiments on the natural product. Our studies concluded that an interchange occurred in the assignment of the benzoyl moiety position with an isoprenyl group in that structure. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：279 / 283

页数：5

共 11 条

[1] Two polyisoprenylated benzophenones from the floral resins of three Clusia species [J].