Microfluidic impedance spectroscopy flow cytometer: Particle size calibration

被引：17

作者：

Cheung, K ^{[1
]}

Gawad, S ^{[1
]}

Renaud, P ^{[1
]}

机构：

[1] Swiss Fed Inst Technol, CH-1015 Lausanne, Switzerland

来源：

MEMS 2004: 17TH IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, TECHNICAL DIGEST | 2004年

关键词：

D O I：

10.1109/MEMS.2004.1290592

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper presents a microfabricated impedance spectroscopy flow cytometer which permits rapid and easy dielectric characterization of cells as they flow in a microchannel. Both a simple theoretical model and a finite element simulation show that the effects of particle size dominate the entire spectrum. Dielectrophoretic forces are used to focus polystyrene beads along the centerline of the channel and decrease the spread in signal amplitude. Measurements of the beads show that size differences of less than 1 gm diameter can be discriminated.

引用

收藏

页码：343 / 346

页数：4

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